| Item Type | Name |
|
Concept
|
Aconitate Hydratase
|
|
Concept
|
Ammonia
|
|
Concept
|
Antigen-Antibody Complex
|
|
Concept
|
Appetite Regulation
|
|
Concept
|
Arcuate Nucleus of Hypothalamus
|
|
Concept
|
Autophagy
|
|
Concept
|
Cyclic AMP
|
|
Concept
|
Adsorption
|
|
Concept
|
Acetylcysteine
|
|
Concept
|
Acyl Coenzyme A
|
|
Concept
|
alpha 1-Antitrypsin
|
|
Concept
|
Bioelectric Energy Sources
|
|
Concept
|
Alleles
|
|
Concept
|
alpha-MSH
|
|
Concept
|
Adrenocorticotropic Hormone
|
|
Concept
|
Energy Intake
|
|
Concept
|
Carboxypeptidases
|
|
Concept
|
Ceramides
|
|
Concept
|
Antigenic Variation
|
|
Concept
|
Calmodulin
|
|
Concept
|
Carbon Dioxide
|
|
Concept
|
Cholecystokinin
|
|
Concept
|
Chondrosarcoma
|
|
Concept
|
Chromatography, DEAE-Cellulose
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Arthritis, Rheumatoid
|
|
Concept
|
Asthma
|
|
Concept
|
Appetite
|
|
Concept
|
Base Sequence
|
|
Concept
|
Cell Count
|
|
Concept
|
Deuterium
|
|
Concept
|
Diabetes Mellitus, Experimental
|
|
Concept
|
Benzene
|
|
Concept
|
Benzopyrans
|
|
Concept
|
Azepines
|
|
Concept
|
Autoantibodies
|
|
Concept
|
Blood Glucose
|
|
Concept
|
Body Temperature
|
|
Concept
|
Bees
|
|
Concept
|
Coleoptera
|
|
Concept
|
Biodegradation, Environmental
|
|
Concept
|
Biomechanical Phenomena
|
|
Concept
|
Body Weight
|
|
Concept
|
Adipose Tissue, Brown
|
|
Concept
|
Butadienes
|
|
Concept
|
Endoribonucleases
|
|
Concept
|
England
|
|
Concept
|
Cattle
|
|
Concept
|
Cell Division
|
|
Concept
|
Cell Separation
|
|
Concept
|
Botulinum Toxins
|
|
Concept
|
Brain Mapping
|
|
Concept
|
Carbachol
|
|
Concept
|
Centrifugation, Density Gradient
|
|
Concept
|
Catalase
|
|
Concept
|
Flavonoids
|
|
Concept
|
Fossil Fuels
|
|
Concept
|
Free Radicals
|
|
Concept
|
Chick Embryo
|
|
Concept
|
Chlorine
|
|
Concept
|
Chlorophyll
|
|
Concept
|
Chromosome Mapping
|
|
Concept
|
Fungi
|
|
Concept
|
Genetic Vectors
|
|
Concept
|
Chromosomes, Human, Pair 5
|
|
Concept
|
Cold Temperature
|
|
Concept
|
Golgi Apparatus
|
|
Concept
|
Creatinine
|
|
Concept
|
Cricetulus
|
|
Concept
|
Chromatography, Ion Exchange
|
|
Concept
|
Collagen
|
|
Concept
|
Diabetes Mellitus, Type 1
|
|
Concept
|
Diabetes Mellitus, Type 2
|
|
Concept
|
Homozygote
|
|
Concept
|
Coronary Circulation
|
|
Concept
|
Hydrogen
|
|
Concept
|
Immunoglobulin M
|
|
Concept
|
Imidazoles
|
|
Concept
|
Dexamethasone
|
|
Concept
|
Dose-Response Relationship, Immunologic
|
|
Concept
|
Diazoxide
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Equipment Design
|
|
Concept
|
Database Management Systems
|
|
Concept
|
Drug Carriers
|
|
Concept
|
Dogs
|
|
Concept
|
Elastin
|
|
Concept
|
Electrophoresis, Polyacrylamide Gel
|
|
Concept
|
Gene Frequency
|
|
Concept
|
Glycogen Synthase
|
|
Concept
|
Electrophysiology
|
|
Concept
|
Epidemiologic Methods
|
|
Concept
|
Enzyme Inhibitors
|
|
Concept
|
London
|
|
Concept
|
Dicyclohexylcarbodiimide
|
|
Concept
|
Chromatography, High Pressure Liquid
|
|
Concept
|
Chromones
|
|
Concept
|
Exons
|
|
Concept
|
Fertilizers
|
|
Concept
|
Malates
|
|
Concept
|
Manganese
|
|
Concept
|
Erythropoietin
|
|
Concept
|
Cocaine
|
|
Concept
|
Cross-Sectional Studies
|
|
Concept
|
Cytomegalovirus
|
|
Concept
|
Double-Blind Method
|
|
Concept
|
Drosophila melanogaster
|
|
Concept
|
Dwarfism
|
|
Concept
|
Fumarates
|
|
Concept
|
Fibroblasts
|
|
Concept
|
Influenza, Human
|
|
Concept
|
Insulinoma
|
|
Concept
|
Interferons
|
|
Concept
|
Introns
|
|
Concept
|
Egtazic Acid
|
|
Concept
|
Electric Conductivity
|
|
Concept
|
Electrophoresis
|
|
Concept
|
Glucagon-Like Peptides
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Mice, Inbred C3H
|
|
Concept
|
Fructose
|
|
Concept
|
Gene Expression Regulation
|
|
Concept
|
Deoxyguanosine
|
|
Concept
|
Genes, Dominant
|
|
Concept
|
Fasting
|
|
Concept
|
Nitrogen
|
|
Concept
|
Obesity
|
|
Concept
|
Oceans and Seas
|
|
Concept
|
Gold
|
|
Concept
|
Histocytochemistry
|
|
Concept
|
Hormone Antagonists
|
|
Concept
|
Oxygen Radioisotopes
|
|
Concept
|
Dopamine
|
|
Concept
|
Drug Combinations
|
|
Concept
|
Hydrogen-Ion Concentration
|
|
Concept
|
Insecticides
|
|
Concept
|
Environmental Monitoring
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Enterovirus Infections
|
|
Concept
|
Environmental Exposure
|
|
Concept
|
Erythrocyte Indices
|
|
Concept
|
Fibrinolysis
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Image Interpretation, Computer-Assisted
|
|
Concept
|
Inhibins
|
|
Concept
|
Interleukin-1
|
|
Concept
|
Fourier Analysis
|
|
Concept
|
Gels
|
|
Concept
|
Isoenzymes
|
|
Concept
|
Glucaric Acid
|
|
Concept
|
Glycerophosphates
|
|
Concept
|
Guanylate Cyclase
|
|
Concept
|
Lacrimal Apparatus
|
|
Concept
|
Light
|
|
Concept
|
Lung Diseases
|
|
Concept
|
Macrophages
|
|
Concept
|
Maleimides
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Metformin
|
|
Concept
|
Leydig Cells
|
|
Concept
|
Gonadotropin-Releasing Hormone
|
|
Concept
|
Hydrolysis
|
|
Concept
|
Mice, Inbred Strains
|
|
Concept
|
Lymphotoxin-alpha
|
|
Concept
|
Mice, Inbred CBA
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Markov Chains
|
|
Concept
|
Extracellular Matrix
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Organ Size
|
|
Concept
|
Glycogen
|
|
Concept
|
Pancreatic Neoplasms
|
|
Concept
|
Pancreatic Elastase
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Radioligand Assay
|
|
Concept
|
Rats, Inbred SHR
|
|
Concept
|
Repetitive Sequences, Nucleic Acid
|
|
Concept
|
Molecular Biology
|
|
Concept
|
Melanocyte-Stimulating Hormones
|
|
Concept
|
Mutation
|
|
Concept
|
Cricetinae
|
|
Concept
|
Hot Temperature
|
|
Concept
|
Paraventricular Hypothalamic Nucleus
|
|
Concept
|
Neutrophils
|
|
Concept
|
Nitric Oxide
|
|
Concept
|
Laminin
|
|
Concept
|
Phosphodiesterase Inhibitors
|
|
Concept
|
Lipopolysaccharides
|
|
Concept
|
Rodentia
|
|
Concept
|
Oocytes
|
|
Concept
|
Ovum
|
|
Concept
|
Oximetry
|
|
Concept
|
Pedigree
|
|
Concept
|
Pattern Recognition, Automated
|
|
Concept
|
Endopeptidases
|
|
Concept
|
Pituitary Gland, Anterior
|
|
Concept
|
Spin Labels
|
|
Concept
|
Petroleum
|
|
Concept
|
Phentolamine
|
|
Concept
|
Phosphoprotein Phosphatases
|
|
Concept
|
Morpholines
|
|
Concept
|
Polymorphism, Genetic
|
|
Concept
|
Oxygen
|
|
Concept
|
Feeding Behavior
|
|
Concept
|
Fetus
|
|
Concept
|
Prealbumin
|
|
Concept
|
Procollagen
|
|
Concept
|
Prediabetic State
|
|
Concept
|
Epoprostenol
|
|
Concept
|
Pituitary Gland
|
|
Concept
|
Plasmids
|
|
Concept
|
Pre-Eclampsia
|
|
Concept
|
Primates
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Proteoglycans
|
|
Concept
|
Pseudogenes
|
|
Concept
|
Protease Inhibitors
|
|
Concept
|
Pyridines
|
|
Concept
|
Foot-and-Mouth Disease
|
|
Concept
|
Forecasting
|
|
Concept
|
Hyperinsulinism
|
|
Concept
|
Triazines
|
|
Concept
|
Glucose Tolerance Test
|
|
Concept
|
Glutamine
|
|
Concept
|
Hypoglycemia
|
|
Concept
|
Immunoglobulin G
|
|
Concept
|
Immunoenzyme Techniques
|
|
Concept
|
Regression Analysis
|
|
Concept
|
Rabbits
|
|
Concept
|
Rats, Zucker
|
|
Concept
|
Receptor, Insulin
|
|
Concept
|
Complement Factor B
|
|
Concept
|
Risk Factors
|
|
Concept
|
Vasoactive Intestinal Peptide
|
|
Concept
|
Pulmonary Circulation
|
|
Concept
|
Insulin Resistance
|
|
Concept
|
Intestinal Absorption
|
|
Concept
|
Somatostatin
|
|
Concept
|
ROC Curve
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Genes, ras
|
|
Concept
|
Rats, Inbred WKY
|
|
Concept
|
Receptors, GABA-A
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
Polymorphism, Restriction Fragment Length
|
|
Concept
|
RNA Splicing
|
|
Concept
|
Cadherins
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Spermatogonia
|
|
Concept
|
Squalene
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
Soil Microbiology
|
|
Concept
|
Swine
|
|
Concept
|
Technology Assessment, Biomedical
|
|
Concept
|
Thymidine
|
|
Concept
|
Hemodynamics
|
|
Concept
|
Heparin
|
|
Concept
|
Humans
|
|
Concept
|
Hypertension, Pulmonary
|
|
Concept
|
Hypothalamic Area, Lateral
|
|
Concept
|
Lisuride
|
|
Concept
|
Body Mass Index
|
|
Concept
|
Incidence
|
|
Concept
|
Cluster Analysis
|
|
Concept
|
Linear Models
|
|
Concept
|
Tomography, Emission-Computed
|
|
Concept
|
Succinates
|
|
Concept
|
Space-Time Clustering
|
|
Concept
|
Tritium
|
|
Concept
|
Interferon Type I
|
|
Concept
|
Thrombosis
|
|
Concept
|
Genome
|
|
Concept
|
Ultrasonography
|
|
Concept
|
Vasoconstriction
|
|
Concept
|
Stroke Volume
|
|
Concept
|
Electric Impedance
|
|
Concept
|
Triglycerides
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Uridine Diphosphate
|
|
Concept
|
Hypertrophy, Right Ventricular
|
|
Concept
|
Testis
|
|
Concept
|
Genetic Variation
|
|
Concept
|
2,2'-Dipyridyl
|
|
Concept
|
Protein Engineering
|
|
Concept
|
Vaccination
|
|
Concept
|
Neprilysin
|
|
Concept
|
Lipase
|
|
Concept
|
Liver Neoplasms, Experimental
|
|
Concept
|
Malonyl Coenzyme A
|
|
Concept
|
Weight Loss
|
|
Concept
|
Randomized Controlled Trials as Topic
|
|
Concept
|
Risk Assessment
|
|
Concept
|
Retroelements
|
|
Concept
|
Cell Culture Techniques
|
|
Concept
|
Oleic Acid
|
|
Concept
|
Enteroendocrine Cells
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Caspases
|
|
Concept
|
Vitamin E
|
|
Concept
|
rac1 GTP-Binding Protein
|
|
Concept
|
Mitogen-Activated Protein Kinases
|
|
Concept
|
Vitamins
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
Aspartic Acid Endopeptidases
|
|
Concept
|
Extracellular Matrix Proteins
|
|
Concept
|
HMGA1a Protein
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Deoxyribonucleases, Type II Site-Specific
|
|
Concept
|
Glucose Clamp Technique
|
|
Concept
|
Antigens, Differentiation, Myelomonocytic
|
|
Concept
|
Prevalence
|
|
Concept
|
Genes, Tumor Suppressor
|
|
Concept
|
Mice, Inbred DBA
|
|
Concept
|
Genes, jun
|
|
Concept
|
Chlamydomonas reinhardtii
|
|
Concept
|
Exercise
|
|
Concept
|
Antigens, CD
|
|
Concept
|
3T3 Cells
|
|
Concept
|
Microinjections
|
|
Concept
|
Milk Proteins
|
|
Concept
|
Cysteine Proteinase Inhibitors
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Rats, Wistar
|
|
Concept
|
Mutagenesis, Site-Directed
|
|
Concept
|
Sequence Alignment
|
|
Concept
|
Drug Delivery Systems
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
RNA Interference
|
|
Concept
|
Ephrin-A1
|
|
Concept
|
Alternative Splicing
|
|
Concept
|
Sequence Analysis, DNA
|
|
Concept
|
Methane
|
|
Concept
|
Methionine
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Mice, Obese
|
|
Concept
|
Microscopy, Electron, Scanning
|
|
Concept
|
Paraffin Embedding
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Amyloid beta-Protein Precursor
|
|
Concept
|
Adipocytes
|
|
Concept
|
Gene Deletion
|
|
Concept
|
MAP Kinase Kinase 1
|
|
Concept
|
MAP Kinase Kinase 2
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Gene Expression Regulation, Developmental
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Thapsigargin
|
|
Concept
|
ras Proteins
|
|
Concept
|
Glucose Intolerance
|
|
Concept
|
Models, Immunological
|
|
Concept
|
Thrombospondin 1
|
|
Concept
|
Neurturin
|
|
Concept
|
Vitronectin
|
|
Concept
|
Ventricular Remodeling
|
|
Concept
|
Staurosporine
|
|
Concept
|
Caspase 3
|
|
Concept
|
MAP Kinase Kinase Kinases
|
|
Concept
|
Calcineurin
|
|
Concept
|
Mutation, Missense
|
|
Concept
|
Melanocortins
|
|
Concept
|
Cross-Over Studies
|
|
Concept
|
Geologic Sediments
|
|
Concept
|
Jurkat Cells
|
|
Concept
|
Gene Knockout Techniques
|
|
Concept
|
GTP Phosphohydrolases
|
|
Concept
|
Nitrogen Dioxide
|
|
Concept
|
Reactive Oxygen Species
|
|
Concept
|
Cathepsin Z
|
|
Concept
|
Genetic Association Studies
|
|
Concept
|
Global Warming
|
|
Concept
|
HMGB Proteins
|
|
Concept
|
Collagen Type VIII
|
|
Concept
|
Primary Cell Culture
|
|
Concept
|
Endostatins
|
|
Concept
|
Carboxypeptidase H
|
|
Concept
|
Proprotein Convertase 2
|
|
Concept
|
Positron-Emission Tomography
|
|
Concept
|
Proteomics
|
|
Concept
|
Basic Reproduction Number
|
|
Concept
|
Collagen Type XVIII
|
|
Concept
|
Luteolin
|
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
|
Concept
|
Area Under Curve
|
|
Concept
|
Microscopy, Confocal
|
|
Concept
|
Ribosomal Protein S6 Kinases
|
|
Concept
|
Proto-Oncogene Proteins c-raf
|
|
Concept
|
Amino Acid Substitution
|
|
Concept
|
Luminescence
|
|
Concept
|
5' Untranslated Regions
|
|
Concept
|
Response Elements
|
|
Concept
|
Neovascularization, Physiologic
|
|
Concept
|
Exopeptidases
|
|
Concept
|
rab3 GTP-Binding Proteins
|
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
|
Concept
|
Matrix Metalloproteinase 3
|
|
Concept
|
Interleukin-1beta
|
|
Concept
|
Nonmuscle Myosin Type IIA
|
|
Concept
|
Platelet Endothelial Cell Adhesion Molecule-1
|
|
Concept
|
Thrombospondins
|
|
Concept
|
I-kappa B Proteins
|
|
Concept
|
rab3A GTP-Binding Protein
|
|
Concept
|
Gene Expression Profiling
|
|
Concept
|
STAT3 Transcription Factor
|
|
Concept
|
Type C Phospholipases
|
|
Concept
|
Pneumonia
|
|
Concept
|
Saccharomyces cerevisiae Proteins
|
|
Concept
|
Electric Power Supplies
|
|
Concept
|
Preoptic Area
|
|
Concept
|
Precipitin Tests
|
|
Concept
|
Pro-Opiomelanocortin
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Mice
|
|
Concept
|
Pyrimidines
|
|
Concept
|
Renin-Angiotensin System
|
|
Concept
|
Radioimmunoassay
|
|
Concept
|
Rats, Inbred Strains
|
|
Concept
|
Ribonucleases
|
|
Concept
|
RNA, Double-Stranded
|
|
Concept
|
Severity of Illness Index
|
|
Concept
|
Glycogen Synthase Kinases
|
|
Concept
|
Glycogen Synthase Kinase 3
|
|
Concept
|
Soil
|
|
Concept
|
Stochastic Processes
|
|
Concept
|
3T3-L1 Cells
|
|
Concept
|
Proprotein Convertase 1
|
|
Concept
|
Furin
|
|
Concept
|
Shc Signaling Adaptor Proteins
|
|
Concept
|
Prolactin-Releasing Hormone
|
|
Concept
|
Rats
|
|
Concept
|
Kruppel-Like Transcription Factors
|
|
Concept
|
Plaque, Amyloid
|
|
Concept
|
Epithelial-Mesenchymal Transition
|
|
Concept
|
High-Throughput Nucleotide Sequencing
|
|
Concept
|
Agricultural Inoculants
|
|
Concept
|
Genotyping Techniques
|
|
Concept
|
Sex Factors
|
|
Concept
|
Spermatocytes
|
|
Concept
|
Vascular Resistance
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Insulin-Secreting Cells
|
|
Concept
|
Chemokine CXCL10
|
|
Concept
|
Temperature
|
|
Concept
|
Immunoblotting
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Models, Statistical
|
|
Concept
|
Nuclear Matrix
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Inositol 1,4,5-Trisphosphate
|
|
Concept
|
PTEN Phosphohydrolase
|
|
Concept
|
Inhibitor of Differentiation Protein 1
|
|
Concept
|
Multivariate Analysis
|
|
Concept
|
Logistic Models
|
|
Concept
|
Survival Analysis
|
|
Concept
|
Transforming Growth Factor alpha
|
|
Concept
|
Cyclins
|
|
Concept
|
Neuroanatomical Tract-Tracing Techniques
|
|
Concept
|
DNA Copy Number Variations
|
|
Concept
|
Thiazoles
|
|
Concept
|
Thyroid Neoplasms
|
|
Concept
|
Islets of Langerhans Transplantation
|
|
Concept
|
Mice, 129 Strain
|
|
Concept
|
Transfection
|
|
Concept
|
Ventromedial Hypothalamic Nucleus
|
|
Concept
|
Blotting, Southern
|
|
Concept
|
Blotting, Northern
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Genetic Therapy
|
|
Concept
|
HLA-DP alpha-Chains
|
|
Concept
|
Single-Strand Specific DNA and RNA Endonucleases
|
|
Concept
|
Gene Expression Regulation, Enzymologic
|
|
Concept
|
Receptors, Glucagon
|
|
Concept
|
Polymerase Chain Reaction
|
|
Concept
|
Ventricular Function, Right
|
|
Concept
|
Anemia, Iron-Deficiency
|
|
Concept
|
Genes, fos
|
|
Concept
|
Magnetic Resonance Imaging, Cine
|
|
Concept
|
DNA Methylation
|
|
Concept
|
GTP-Binding Proteins
|
|
Concept
|
NADPH Oxidases
|
|
Concept
|
Interleukin-1 Receptor-Associated Kinases
|
|
Concept
|
Leukocyte Common Antigens
|
|
Concept
|
Dietary Supplements
|
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
|
Concept
|
Calcium-Calmodulin-Dependent Protein Kinases
|
|
Concept
|
Receptors, GABA
|
|
Concept
|
In Situ Nick-End Labeling
|
|
Concept
|
Comet Assay
|
|
Concept
|
cdc42 GTP-Binding Protein
|
|
Concept
|
Son of Sevenless Protein, Drosophila
|
|
Concept
|
Imaging, Three-Dimensional
|
|
Concept
|
Gene Knockdown Techniques
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Leukocyte Elastase
|
|
Concept
|
Body Patterning
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Untranslated Regions
|
|
Concept
|
Monomeric GTP-Binding Proteins
|
|
Concept
|
GTPase-Activating Proteins
|
|
Concept
|
JNK Mitogen-Activated Protein Kinases
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
STAT5 Transcription Factor
|
|
Concept
|
GRB2 Adaptor Protein
|
|
Concept
|
Glucagon-Like Peptide 1
|
|
Concept
|
Transcriptome
|
|
Concept
|
Janus Kinase 2
|
|
Concept
|
Protein Tyrosine Phosphatase, Non-Receptor Type 1
|
|
Concept
|
Genome-Wide Association Study
|
|
Concept
|
AMP-Activated Protein Kinases
|
|
Concept
|
Insulin Receptor Substrate Proteins
|
|
Concept
|
Hep G2 Cells
|
|
Concept
|
Pathology, Molecular
|
|
Concept
|
Mendelian Randomization Analysis
|
|
Concept
|
Climate Change
|
|
Concept
|
Dynamins
|
|
Concept
|
Fluorescence Recovery After Photobleaching
|
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
|
Concept
|
Kaempferols
|
|
Concept
|
Pancreas, Exocrine
|
|
Concept
|
Cell Size
|
|
Concept
|
Cell Shape
|
|
Concept
|
Dendrimers
|
|
Concept
|
Suppressor of Cytokine Signaling Proteins
|
|
Concept
|
ADAM Proteins
|
|
Concept
|
Kaplan-Meier Estimate
|
|
Concept
|
Amyloid Precursor Protein Secretases
|
|
Concept
|
rho-Associated Kinases
|
|
Concept
|
National Heart, Lung, and Blood Institute (U.S.)
|
|
Concept
|
Growth Differentiation Factor 2
|
|
Concept
|
Gene Knock-In Techniques
|
|
Concept
|
Cyclin D2
|
|
Concept
|
Islet Amyloid Polypeptide
|
|
Concept
|
Alzheimer Disease
|
|
Concept
|
Antibodies
|
|
Concept
|
Autopsy
|
|
Concept
|
Benzene Derivatives
|
|
Concept
|
Binding, Competitive
|
|
Concept
|
Blood Chemical Analysis
|
|
Concept
|
Cations
|
|
Concept
|
Cell Survival
|
|
Concept
|
Chromatin
|
|
Concept
|
Chromosomes, Human
|
|
Concept
|
Cloning, Molecular
|
|
Concept
|
Diabetes Mellitus
|
|
Concept
|
Dietary Fats
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Dorsomedial Hypothalamic Nucleus
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Epidermal Growth Factor
|
|
Concept
|
Erythrocytes
|
|
Concept
|
Esterases
|
|
Concept
|
Fluorescent Dyes
|
|
Concept
|
Follow-Up Studies
|
|
Concept
|
Foxes
|
|
Concept
|
Gasoline
|
|
Concept
|
Genotype
|
|
Concept
|
Glucose
|
|
Concept
|
Guanosine Diphosphate
|
|
Concept
|
Heterozygote
|
|
Concept
|
Hyperglycemia
|
|
Concept
|
Hypothalamus
|
|
Concept
|
Immunoglobulins
|
|
Concept
|
Kinetics
|
|
Concept
|
Genetic Linkage
|
|
Concept
|
Magnetic Resonance Imaging
|
|
Concept
|
Mesocricetus
|
|
Concept
|
Microscopy, Fluorescence
|
|
Concept
|
Microtomy
|
|
Concept
|
Nicotine
|
|
Concept
|
Odontogenesis
|
|
Concept
|
Palmitoyl Coenzyme A
|
|
Concept
|
Phosphates
|
|
Concept
|
Prospective Studies
|
|
Concept
|
Protons
|
|
Concept
|
Herpesvirus 1, Suid
|
|
Concept
|
Pulmonary Embolism
|
|
Concept
|
Rats, Mutant Strains
|
|
Concept
|
Recombinant Fusion Proteins
|
|
Concept
|
Retrospective Studies
|
|
Concept
|
Serine Endopeptidases
|
|
Concept
|
Spermatozoa
|
|
Concept
|
Sphingosine
|
|
Concept
|
Subtilisins
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Thorium
|
|
Concept
|
Thymine
|
|
Concept
|
Toluene
|
|
Concept
|
Wales
|
|
Concept
|
Gastric Bypass
|
|
Concept
|
Transcriptional Activation
|
|
Concept
|
Gene Expression Regulation, Neoplastic
|
|
Concept
|
Granulocyte-Macrophage Colony-Stimulating Factor
|
|
Concept
|
Cytokines
|
|
Concept
|
Kallikrein-Kinin System
|
|
Concept
|
Mice, Inbred NOD
|
|
Concept
|
Sequence Analysis, RNA
|
|
Concept
|
Hydroxyl Radical
|
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
|
Concept
|
Electroporation
|
|
Concept
|
Coculture Techniques
|
|
Concept
|
Computational Biology
|
|
Concept
|
Peptide YY
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
3-Hydroxybutyric Acid
|
|
Concept
|
Polymorphism, Single Nucleotide
|
|
Concept
|
ADP-Ribosylation Factors
|
|
Concept
|
Collagen Type IV
|
|
Concept
|
Activins
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Quantitative Trait Loci
|
|
Concept
|
Genetic Drift
|
|
Concept
|
Epigenesis, Genetic
|
|
Concept
|
Microscopy, Electron, Transmission
|
|
Concept
|
Protein Kinase Inhibitors
|
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
|
Concept
|
Overweight
|
|
Concept
|
Aquaporin 1
|
|
Concept
|
Environmental Restoration and Remediation
|
|
Concept
|
Caspase 9
|
|
Concept
|
Glucagon-Like Peptide 2
|
|
Concept
|
Receptor-Like Protein Tyrosine Phosphatases, Class 8
|
|
Concept
|
Ubiquitination
|
|
Concept
|
Infusions, Subcutaneous
|
|
Concept
|
Growth Differentiation Factors
|
|
Concept
|
Growth Differentiation Factor 15
|
|
Concept
|
HLA-DP beta-Chains
|
|
Concept
|
alpha-2-HS-Glycoprotein
|
|
Academic Article
|
Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line.
|
|
Academic Article
|
A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells.
|
|
Academic Article
|
Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells.
|
|
Academic Article
|
Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins.
|
|
Academic Article
|
Preferential cleavage of des-31,32-proinsulin over intact proinsulin by the insulin secretory granule type II endopeptidase. Implication of a favored route for prohormone processing.
|
|
Academic Article
|
Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.
|
|
Academic Article
|
Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells).
|
|
Academic Article
|
Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).
|
|
Academic Article
|
Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation.
|
|
Academic Article
|
Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis.
|
|
Academic Article
|
Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation.
|
|
Academic Article
|
A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties.
|
|
Academic Article
|
Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells.
|
|
Academic Article
|
Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
|
|
Academic Article
|
Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes?
|
|
Academic Article
|
A low-affinity Ca2+-dependent association of calmodulin with the Rab3A effector domain inversely correlates with insulin exocytosis.
|
|
Academic Article
|
Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1).
|
|
Academic Article
|
Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells.
|
|
Academic Article
|
Syncollin inhibits regulated corticotropin secretion from AtT-20 cells through a reduction in the secretory vesicle population.
|
|
Academic Article
|
Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport.
|
|
Academic Article
|
Type 2 diabetes-a matter of beta-cell life and death?
|
|
Academic Article
|
Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation.
|
|
Academic Article
|
Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells.
|
|
Academic Article
|
Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons.
|
|
Academic Article
|
Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression.
|
|
Academic Article
|
A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation.
|
|
Academic Article
|
Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.
|
|
Academic Article
|
The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion.
|
|
Academic Article
|
The inhibition of proinsulin-processing endopeptidase activities by active-site-directed peptides.
|
|
Academic Article
|
Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance.
|
|
Academic Article
|
Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3ß independent of JNK activation.
|
|
Academic Article
|
Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway.
|
|
Academic Article
|
AMP-activated protein kinase attenuates nitric oxide-induced beta-cell death.
|
|
Academic Article
|
Formation of a human ß-cell population within pancreatic islets is set early in life.
|
|
Academic Article
|
Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases.
|
|
Academic Article
|
High-performance liquid chromatography (HPLC): a rapid, flexible and sensitive method for separating islet proinsulin and insulin.
|
|
Academic Article
|
2-5A-dependent endoribonuclease activity and effects of A2'p5'A2'p5'A (2-5A core) in mouse pancreatic islets.
|
|
Academic Article
|
Glucose stimulates the biosynthesis of rat I and II insulin to an equal extent in isolated pancreatic islets.
|
|
Academic Article
|
A Kex2-related endopeptidase activity present in rat liver specifically processes the insulin proreceptor.
|
|
Academic Article
|
Mechanism of action of glucagon-like peptide-2 to increase IGF-I mRNA in intestinal subepithelial fibroblasts.
|
|
Academic Article
|
The intracellular handling of insulin-related peptides in isolated pancreatic islets. Evidence for differential rates of degradation of insulin and C-peptide.
|
|
Academic Article
|
Long-term biochemical changes in the islets of Langerhans in mice following infection with encephalomyocarditis virus.
|
|
Academic Article
|
Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1.
|
|
Academic Article
|
Molecular insights into insulin action and secretion.
|
|
Academic Article
|
Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis.
|
|
Academic Article
|
IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells.
|
|
Academic Article
|
Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets.
|
|
Academic Article
|
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.
|
|
Academic Article
|
Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve.
|
|
Academic Article
|
Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1.
|
|
Academic Article
|
Effects of glucose and D-3-hydroxybutyrate on human pancreatic islet cell function.
|
|
Academic Article
|
Proinsulin endopeptidase substrate specificities defined by site-directed mutagenesis of proinsulin.
|
|
Academic Article
|
IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication.
|
|
Academic Article
|
Direct innervation of GnRH neurons by metabolic- and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleus.
|
|
Academic Article
|
Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells.
|
|
Academic Article
|
Intracellular signalling. Key enzyme in leptin-induced anorexia.
|
|
Academic Article
|
Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala.
|
|
Academic Article
|
ß1 integrin is a crucial regulator of pancreatic ß-cell expansion.
|
|
Academic Article
|
Direct innervation and modulation of orexin neurons by lateral hypothalamic LepRb neurons.
|
|
Academic Article
|
ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.
|
|
Academic Article
|
Absolute quantification of myocardial blood flow with H(2)(15)O and 3-dimensional PET: an experimental validation.
|
|
Academic Article
|
RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.
|
|
Academic Article
|
Control of food intake and energy expenditure by Nos1 neurons of the paraventricular hypothalamus.
|
|
Academic Article
|
Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity.
|
|
Academic Article
|
Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension.
|
|
Academic Article
|
Machine Learning of Three-dimensional Right Ventricular Motion Enables Outcome Prediction in Pulmonary Hypertension: A Cardiac MR Imaging Study.
|
|
Academic Article
|
Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-ß in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension.
|
|
Academic Article
|
Ca(2+)-regulated serine protease associated with the nuclear scaffold.
|
|
Academic Article
|
Solar energy: principles and possibilities.
|
|
Academic Article
|
The c-propeptide of type II procollagen binds to the enhancer region of the type II procollagen gene and regulates its transcription.
|
|
Academic Article
|
Rising sea levels - by how much, and why?
|
|
Academic Article
|
Plastic pollution and potential solutions.
|
|
Academic Article
|
Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits.
|
|
Academic Article
|
Perovskites - some snapshots of recent developments.
|
|
Academic Article
|
Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension.
|
|
Academic Article
|
An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28.
|
|
Academic Article
|
Unpaired electrons as probes of catalytic systems.
|
|
Academic Article
|
Targeting Free Radicals in Oxidative Stress-Related Human Diseases.
|
|
Academic Article
|
Transepithelial transport of poly(amidoamine) dendrimers across Caco-2 cell monolayers.
|
|
Academic Article
|
Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights.
|
|
Academic Article
|
"Spin-labelling" with the second hydrogen radioisotope: radicals formed from squalene by muonium addition.
|
|
Academic Article
|
Recent advances in pulmonary arterial hypertension.
|
|
Academic Article
|
Multicomponent spectroscopic investigations of salivary antioxidant consumption by an oral rinse preparation containing the stable free radical species chlorine dioxide (ClO2.).
|
|
Academic Article
|
Feeding and healing the world: through regenerative agriculture and permaculture.
|
|
Academic Article
|
A new human (psycho)pharmacology tool: the multiple organs coincidences counter (MOCC).
|
|
Academic Article
|
Novel catalysts for water splitting and green chemistry applications.
|
|
Academic Article
|
Oil from algae; salvation from peak oil?
|
|
Academic Article
|
The whispering world of plants: 'The Wood Wide Web'.
|
|
Academic Article
|
The effect of superspreading on epidemic outbreak size distributions.
|
|
Academic Article
|
Subcellular resolution mapping of endogenous cytokine secretion by nano-plasmonic-resonator sensor array.
|
|
Academic Article
|
The human genome contains a pseudogene for the Mr=32,000 laminin binding protein.
|
|
Academic Article
|
Biochar, and its potential contribution to improving soil quality and carbon capture.
|
|
Academic Article
|
Muon spectroscopy applied to biological systems: a study of thiyl radicals, RS.
|
|
Academic Article
|
"Vibrational bonding": a new type of chemical bond is discovered.
|
|
Academic Article
|
Role of oxygen radicals in DNA damage and cancer incidence.
|
|
Academic Article
|
Arsenic: toxicity, oxidative stress and human disease.
|
|
Academic Article
|
Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity.
|
|
Academic Article
|
Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1.
|
|
Academic Article
|
Identification of the Novel Tooth-Specific Transcription Factor AmeloD.
|
|
Academic Article
|
Iron deficiency in pulmonary arterial hypertension: a potential therapeutic target.
|
|
Academic Article
|
The oil question: nature and prognosis.
|
|
Academic Article
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PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE.
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Current Commentary Recent Developments in Solar Energy Applications based on Perovskites: A Current Commentary.
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Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension.
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Redox- and non-redox-metal-induced formation of free radicals and their role in human disease.
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Shortage of resources for renewable energy and food production.
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Electron spin resonance. Part two: a diagnostic method in the environmental sciences.
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Pancreatic ß-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes.
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The influence of viral infection on a plankton ecosystem undergoing nutrient enrichment.
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Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
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Metabolic pathways associated with right ventricular adaptation to pulmonary hypertension: 3D analysis of cardiac magnetic resonance imaging.
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Human PAH is characterized by a pattern of lipid-related insulin resistance.
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The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.
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Inhibition of upper small intestinal mTOR lowers plasma glucose levels by inhibiting glucose production.
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Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: a UK cohort study analysis.
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Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice.
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Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia.
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Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.
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Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension.
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Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension.
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Endangered elements, critical raw materials and conflict minerals.
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Are insect species imperilled? Critical factors and prevailing evidence for a potential global loss of the entomofauna: A current commentary.
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Only 12 years left to readjust for the 1.5-degree climate change option - Says International Panel on Climate Change report: Current commentary.
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Solving the plastic problem: From cradle to grave, to reincarnation.
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Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding.
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Targeting Vessel Formation in Pulmonary Arterial Hypertension: Is the Endostatin-Id1-Thrombospondin 1 Pathway a New Hope?
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Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension.
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Leptin receptor-expressing nucleus tractus solitarius neurons suppress food intake independently of GLP1 in mice.
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The application of 'omics' to pulmonary arterial hypertension.
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Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice.
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A fluorescent timer reporter enables sorting of insulin secretory granules by age.
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Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome.
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Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis.
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Author Correction: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension.
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Plasma metabolomics exhibit response to therapy in chronic thromboembolic pulmonary hypertension.
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Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension.
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The cancer hypothesis of pulmonary arterial hypertension: are polyamines the new Warburg?
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Bayesian Inference Associates Rare KDR Variants with Specific Phenotypes in Pulmonary Arterial Hypertension.
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Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice.
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A fluorescent timer reporter enables sorting of insulin secretory granules by age.
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Antioxidant vs. Prooxidant Properties of the Flavonoid, Kaempferol, in the Presence of Cu(II) Ions: A ROS-Scavenging Activity, Fenton Reaction and DNA Damage Study.
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The pathophysiological role of novel pulmonary arterial hypertension gene SOX17.
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Supplementation with Iron in Pulmonary Arterial Hypertension. Two Randomized Crossover Trials.
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A genetic map of the mouse dorsal vagal complex and its role in obesity.
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Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial.
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NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification: JACC State-of-the-Art Review.
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A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach.
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Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency.
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NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity.
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Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension.
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NMDARs Drive the Expression of Neuropsychiatric Disorder Risk Genes Within GABAergic Interneuron Subtypes in the Juvenile Brain.
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World scientists' warnings into action, local to global.
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Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ß-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries.
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The effect of Luteolin on DNA damage mediated by a copper catalyzed Fenton reaction.
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BAd-CRISPR: Inducible gene knockout in interscapular brown adipose tissue of adult mice.
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Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood.
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Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension.
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Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain.
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Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension.
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Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension.
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Calcineurin/NFATc2 and PI3K/AKT signaling maintains ß-cell identity and function during metabolic and inflammatory stress.
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Harnessing Big Data to Advance Treatment and Understanding of Pulmonary Hypertension.
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Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life.
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Who knew? PPARs may act in the brain too.
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An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis.
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Cytokines as prognostic biomarkers in pulmonary arterial hypertension.
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PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension.
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Author Correction: Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood.
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Circulating markers of inflammation and angiogenesis and clinical outcomes across subtypes of pulmonary arterial hypertension.
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Essential metals in health and disease.
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High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity.
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Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension.
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Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity.
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Concept
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Cell Plasticity
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Concept
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Glucagon-Like Peptide-1 Receptor
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Concept
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Glucagon-Like Peptide-2 Receptor
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Concept
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Clinical Studies as Topic
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Concept
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Orexins
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Concept
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Liraglutide
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Concept
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Machine Learning
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Concept
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Suppressor of Cytokine Signaling 3 Protein
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Concept
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ADAM10 Protein
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Concept
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ADAMTS13 Protein
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Concept
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Src Homology 2 Domain-Containing, Transforming Protein 1
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Concept
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Proprotein Convertase 9
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Concept
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Glycogen Synthase Kinase 3 beta
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Concept
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Soluble Guanylyl Cyclase
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Concept
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Fibrillin-1
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Concept
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Circulating MicroRNA
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Concept
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Whole Genome Sequencing
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Concept
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Dietary Sugars
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Concept
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Human Genetics
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Concept
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Regulatory-Associated Protein of mTOR
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Concept
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Arterial Pressure
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Concept
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Netrins
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Concept
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Epidemiological Monitoring
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Concept
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RNA, Long Noncoding
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Concept
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Plant Development
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Concept
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Pediatric Obesity
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Concept
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Gene Ontology
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Concept
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CRISPR-Cas Systems
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Concept
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3-Phosphoinositide-Dependent Protein Kinases
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Concept
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Calcineurin Inhibitors
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Concept
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Familial Primary Pulmonary Hypertension
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Concept
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Vascular Remodeling
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Grant
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Central Control of Pancreatic Islet Function
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Grant
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Western Region Islet Study Group
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Grant
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Metabolic Control of Proinsulin Biosynthesis Translation
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Grant
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Metabolic Control of Proinsulin Biosynthesis Translation
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Academic Article
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Restoring polyamine levels by supplementation of spermidine modulates hepatic immune landscape in murine model of NASH.
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Academic Article
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Serum and Pulmonary Expression Profiles of the Activin Signaling System in Pulmonary Arterial Hypertension.
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Academic Article
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SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension.
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Academic Article
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The role of redox active copper(II) on antioxidant properties of the flavonoid baicalein: DNA protection under Cu(II)-Fenton reaction and Cu(II)-ascorbate system conditions.
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World scientists' warning: The behavioural crisis driving ecological overshoot.
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The SOX17 phenotype in pulmonary arterial hypertension: lessons for pathobiology and clinical management.
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Academic Article
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Response by Walters et al to Letter Regarding Article, "SOX17 Enhancer Variants Disrupt Transcription Factor Binding and Enhancer Inactivity Drives Pulmonary Hypertension".
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Academic Article
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Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension.
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Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension.
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Academic Article
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Hepatic Glucagon Action - Beyond Glucose Mobilization.
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Academic Article
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Multi-biobank summary data Mendelian randomisation does not support a causal effect of IL-6 signalling on risk of pulmonary arterial hypertension.
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Academic Article
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Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension.
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Academic Article
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Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism.
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